{
  "$defs": {
    "Assay": {
      "description": "[OBI, OBI:0000070, assay] A planned process that has the objective to produce information\nabout a material entity by examining it.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "assay",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "An assay identifier that uniquely identifies the assay in repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the assay. It SHOULD be unique in a study.",
          "title": "Name"
        },
        "metadata_file_ref": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the metadata file describing the assay.",
          "title": "Metadata File Ref"
        },
        "technology_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the technology type CV term object.",
          "title": "Technology Type Ref"
        },
        "assay_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the assay type CV term object.",
          "title": "Assay Type Ref"
        },
        "measurement_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the measurement type CV term object.",
          "title": "Measurement Type Ref"
        },
        "omics_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the omics type CV term object.",
          "title": "Omics Type Ref"
        },
        "protocol_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id properties of protocols used in assay. A protocol is a defined and standardized procedure followed to collect, prepare, or analyze biological samples.",
          "title": "Protocol Refs"
        },
        "sample_run_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of sample run object IDs associated with the assay.",
          "title": "Sample Run Refs"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Assay",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "BaseLabeledMhdModel": {
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "base-mhd-model",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        }
      },
      "title": "BaseLabeledMhdModel",
      "type": "object"
    },
    "BasicAssay": {
      "description": "Basic analytical assay node representing an experimental measurement procedure.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "assay",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "An assay identifier that uniquely identifies the assay in repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the assay. It SHOULD be unique in a study.",
          "title": "Name"
        },
        "metadata_file_ref": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the metadata file describing the assay.",
          "title": "Metadata File Ref"
        },
        "technology_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the technology type CV term object.",
          "title": "Technology Type Ref"
        },
        "assay_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the assay type CV term object.",
          "title": "Assay Type Ref"
        },
        "measurement_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the measurement type CV term object.",
          "title": "Measurement Type Ref"
        },
        "omics_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the omics type CV term object.",
          "title": "Omics Type Ref"
        },
        "protocol_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id properties of protocols used in assay. A protocol is a defined and standardized procedure followed to collect, prepare, or analyze biological samples.",
          "title": "Protocol Refs"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "BasicAssay",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "CvDefinition": {
      "properties": {
        "label": {
          "default": "",
          "title": "Label",
          "type": "string"
        },
        "name": {
          "default": "",
          "title": "Name",
          "type": "string"
        },
        "uri": {
          "default": "",
          "title": "Uri",
          "type": "string"
        },
        "prefix": {
          "default": "",
          "title": "Prefix",
          "type": "string"
        },
        "alternative_labels": {
          "anyOf": [
            {
              "items": {
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Alternative Labels"
        },
        "alternative_prefixes": {
          "anyOf": [
            {
              "items": {
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Alternative Prefixes"
        }
      },
      "title": "CvDefinition",
      "type": "object"
    },
    "CvTerm": {
      "properties": {
        "source": {
          "default": "",
          "description": "Ontology source name.",
          "title": "Source",
          "type": "string"
        },
        "accession": {
          "default": "",
          "description": "Accession number of CV term in compact URI format.",
          "title": "Accession",
          "type": "string"
        },
        "name": {
          "default": "",
          "description": "Label of CV term.",
          "title": "Name",
          "type": "string"
        }
      },
      "title": "CvTerm",
      "type": "object"
    },
    "CvTermObject": {
      "description": "Controlled Vocabulary (CV) term object node in the dataset graph.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "cv-term",
          "description": "The type property identifies type of the CV Term object",
          "title": "Type"
        },
        "source": {
          "default": "",
          "description": "Ontology source name.",
          "title": "Source",
          "type": "string"
        },
        "accession": {
          "default": "",
          "description": "Accession number of CV term in compact URI format.",
          "title": "Accession",
          "type": "string"
        },
        "name": {
          "default": "",
          "description": "Label of CV term.",
          "title": "Name",
          "type": "string"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        }
      },
      "title": "CvTermObject",
      "type": "object",
      "unique_value_contribution": [
        "source",
        "accession",
        "name"
      ]
    },
    "CvTermValue": {
      "properties": {
        "value": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "integer"
            },
            {
              "type": "number"
            },
            {
              "pattern": "^(?!^[-+.]*$)[+-]?0*\\d*\\.?\\d*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Value of CV term.",
          "title": "Value"
        },
        "unit": {
          "anyOf": [
            {
              "$ref": "#/$defs/UnitCvTerm"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Unit CV term if value has a unit.",
          "title": "Unit"
        },
        "source": {
          "default": "",
          "description": "Ontology source name.",
          "title": "Source",
          "type": "string"
        },
        "accession": {
          "default": "",
          "description": "Accession number of CV term in compact URI format.",
          "title": "Accession",
          "type": "string"
        },
        "name": {
          "default": "",
          "description": "Label of CV term.",
          "title": "Name",
          "type": "string"
        }
      },
      "title": "CvTermValue",
      "type": "object"
    },
    "CvTermValueObject": {
      "description": "Controlled Vocabulary (CV) term value object node with quantitative or string value.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "cv-term-value",
          "description": "The type property identifies type of the CV Term Value object",
          "title": "Type"
        },
        "value": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "integer"
            },
            {
              "type": "number"
            },
            {
              "pattern": "^(?!^[-+.]*$)[+-]?0*\\d*\\.?\\d*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Value of CV term.",
          "title": "Value"
        },
        "unit": {
          "anyOf": [
            {
              "$ref": "#/$defs/UnitCvTerm"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Unit CV term if value has a unit.",
          "title": "Unit"
        },
        "source": {
          "default": "",
          "description": "Ontology source name.",
          "title": "Source",
          "type": "string"
        },
        "accession": {
          "default": "",
          "description": "Accession number of CV term in compact URI format.",
          "title": "Accession",
          "type": "string"
        },
        "name": {
          "default": "",
          "description": "Label of CV term.",
          "title": "Name",
          "type": "string"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        }
      },
      "title": "CvTermValueObject",
      "type": "object",
      "unique_value_contribution": [
        "source",
        "accession",
        "name",
        "value",
        "unit"
      ]
    },
    "DerivedDataFile": {
      "description": "[MS, MS:1003084, processed data file]\nFile that contains data that has been substantially processed or\ntransformed from what was originally acquired by an instrument.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "derived-data-file",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the file in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the file. File MUST be a file (not folder or link).It MAY be relative path (e.g., FILES/study.txt) or a file in a compressed file (e.g., FILES/study.zip#data/metadata.tsv).",
          "title": "Name"
        },
        "size": {
          "anyOf": [
            {
              "type": "integer"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The size of the file in bytes, representing the total amount of data contained in the file.",
          "title": "Size"
        },
        "hash_sha256": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The SHA-256 cryptographic hash of the file content, used to verify file integrity and ensure that the file has not been altered.",
          "title": "Hash Sha256"
        },
        "format_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to store the contents of the file, typically indicated by its extension (e.g., .txt, .csv, .mzML, .raw, etc.).",
          "title": "Format Ref"
        },
        "compression_format_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to compress the contents of the file, typically indicated by its extension (e.g., .zip, .tar, .gz, etc.). List item order shows order of compressions. e.g. [tar format, gzip format] for tar.gz",
          "title": "Compression Format Refs"
        },
        "extension": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The extension of file. It MUST contain all extensions (e.g., .raw, .mzML, .d.zip, .raw.zip, etc.).",
          "title": "Extension"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "DerivedDataFile",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "KeyValue": {
      "properties": {
        "key": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "string"
            },
            {
              "$ref": "#/$defs/CvTerm"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Key"
        },
        "value": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "string"
            },
            {
              "type": "integer"
            },
            {
              "format": "date-time",
              "type": "string"
            },
            {
              "type": "boolean"
            },
            {
              "type": "number"
            },
            {
              "$ref": "#/$defs/CvTerm"
            },
            {
              "$ref": "#/$defs/CvTermValue"
            },
            {
              "$ref": "#/$defs/QuantitativeValue"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Value"
        }
      },
      "title": "KeyValue",
      "type": "object"
    },
    "Metabolite": {
      "description": "Any intermediate or product resulting from metabolism.\nThe term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. [CHEBI, CHEBI:25212, metabolite]",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "metabolite",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name or chemical label of the metabolite.",
          "title": "Name"
        }
      },
      "title": "Metabolite",
      "type": "object",
      "unique_value_contribution": [
        "name"
      ]
    },
    "MetadataFile": {
      "description": "Metadata file (e.g., SDRF, ISA-Tab) describing experimental design and samples.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "metadata-file",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the file in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the file. File MUST be a file (not folder or link).It MAY be relative path (e.g., FILES/study.txt) or a file in a compressed file (e.g., FILES/study.zip#data/metadata.tsv).",
          "title": "Name"
        },
        "size": {
          "anyOf": [
            {
              "type": "integer"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The size of the file in bytes, representing the total amount of data contained in the file.",
          "title": "Size"
        },
        "hash_sha256": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The SHA-256 cryptographic hash of the file content, used to verify file integrity and ensure that the file has not been altered.",
          "title": "Hash Sha256"
        },
        "format_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to store the contents of the file, typically indicated by its extension (e.g., .txt, .csv, .mzML, .raw, etc.).",
          "title": "Format Ref"
        },
        "compression_format_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to compress the contents of the file, typically indicated by its extension (e.g., .zip, .tar, .gz, etc.). List item order shows order of compressions. e.g. [tar format, gzip format] for tar.gz",
          "title": "Compression Format Refs"
        },
        "extension": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The extension of file. It MUST contain all extensions (e.g., .raw, .mzML, .d.zip, .raw.zip, etc.).",
          "title": "Extension"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "MetadataFile",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "MhdGraph": {
      "properties": {
        "start_item_refs": {
          "default": [],
          "items": {
            "anyOf": [
              {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              {
                "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              {
                "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              }
            ]
          },
          "title": "Start Item Refs",
          "type": "array"
        },
        "nodes": {
          "default": [],
          "items": {
            "anyOf": [
              {
                "$ref": "#/$defs/CvTermValueObject"
              },
              {
                "$ref": "#/$defs/CvTermObject"
              },
              {
                "$ref": "#/$defs/Organization"
              },
              {
                "$ref": "#/$defs/Person"
              },
              {
                "$ref": "#/$defs/Project"
              },
              {
                "$ref": "#/$defs/Study"
              },
              {
                "$ref": "#/$defs/Protocol"
              },
              {
                "$ref": "#/$defs/Publication"
              },
              {
                "$ref": "#/$defs/BasicAssay"
              },
              {
                "$ref": "#/$defs/Assay"
              },
              {
                "$ref": "#/$defs/Specimen"
              },
              {
                "$ref": "#/$defs/Subject"
              },
              {
                "$ref": "#/$defs/Sample"
              },
              {
                "$ref": "#/$defs/SampleRun"
              },
              {
                "$ref": "#/$defs/SampleRunConfiguration"
              },
              {
                "$ref": "#/$defs/Metabolite"
              },
              {
                "$ref": "#/$defs/MetadataFile"
              },
              {
                "$ref": "#/$defs/ResultFile"
              },
              {
                "$ref": "#/$defs/RawDataFile"
              },
              {
                "$ref": "#/$defs/DerivedDataFile"
              },
              {
                "$ref": "#/$defs/SupplementaryFile"
              },
              {
                "$ref": "#/$defs/BaseLabeledMhdModel"
              }
            ],
            "description": "Possible Node Type"
          },
          "title": "Nodes",
          "type": "array"
        },
        "relationships": {
          "default": [],
          "items": {
            "$ref": "#/$defs/Relationship"
          },
          "title": "Relationships",
          "type": "array"
        }
      },
      "title": "MhdGraph",
      "type": "object"
    },
    "Organization": {
      "description": "An institution, company, university, or department associated with a study or contact.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "organization",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the organization in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "description": "Name of the organization.",
          "minLength": 2,
          "title": "Name",
          "type": "string"
        },
        "ror_id": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Research Organization Registry (ROR) identifier.",
          "title": "Ror Id"
        },
        "department": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Department within the organization.",
          "title": "Department"
        },
        "unit": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Sub-unit or division within the organization or department.",
          "title": "Unit"
        },
        "address": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Postal address of the organization.",
          "title": "Address"
        }
      },
      "required": [
        "repository_identifier",
        "name"
      ],
      "title": "Organization",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Person": {
      "description": "An individual human being (e.g. author, submitter, principal investigator).",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "person",
          "description": "The value of this property MUST be 'person'",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the person in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "full_name": {
          "anyOf": [
            {
              "minLength": 2,
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Full name of person",
          "title": "Full Name"
        },
        "orcid": {
          "anyOf": [
            {
              "pattern": "^[0-9]{4}-[0-9]{4}-[0-9]{4}-[0-9]{3}[X0-9]$",
              "title": "ORCID",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "ORCID identifier of person",
          "examples": [
            "1234-0001-8473-1713",
            "1234-0001-8473-171X"
          ],
          "title": "ORCID"
        },
        "email_list": {
          "anyOf": [
            {
              "items": {
                "format": "email",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Email addresses of person",
          "title": "Email List"
        },
        "phone_list": {
          "anyOf": [
            {
              "items": {
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Phone number of person (with international country code)",
          "examples": [
            [
              "+449340917271",
              "00449340917271"
            ]
          ],
          "title": "Phone List"
        },
        "address_list": {
          "anyOf": [
            {
              "items": {
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Addresses of person",
          "title": "Address List"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Person",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier",
        "full_name",
        "orcid"
      ]
    },
    "Project": {
      "description": "An overarching research project encompassing one or more studies.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "project",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "title": {
          "anyOf": [
            {
              "minLength": 2,
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Title of the project.",
          "title": "Title"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the project in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "description": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Summary description of the project goals and scope.",
          "title": "Description"
        },
        "grant_identifier_list": {
          "anyOf": [
            {
              "items": {
                "minLength": 2,
                "title": "Grant Identifier",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of grant identifiers funding the project.",
          "title": "Grant Identifier List"
        },
        "doi": {
          "anyOf": [
            {
              "pattern": "^10[.].+/.+$",
              "title": "DOI",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Digital Object Identifier (DOI) assigned to the project.",
          "title": "Doi"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Project",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Protocol": {
      "description": "A defined and standardized procedure followed to collect, prepare, or analyze samples.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "protocol",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the protocol in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name or title of the protocol.",
          "title": "Name"
        },
        "protocol_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the protocol type CV term object.",
          "title": "Protocol Type Ref"
        },
        "description": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Detailed description of the protocol procedure.",
          "title": "Description"
        },
        "parameter_definition_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of parameter definition object IDs associated with the protocol.",
          "title": "Parameter Definition Refs"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Protocol",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Publication": {
      "description": "A document that is the output of a publishing process. [IAO, IAO:0000311, publication]",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "publication",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "title": {
          "description": "Title of the publication.",
          "minLength": 10,
          "title": "Title",
          "type": "string"
        },
        "doi": {
          "description": "Digital Object Identifier (DOI) for the publication.",
          "pattern": "^10[.].+/.+$",
          "title": "DOI",
          "type": "string"
        },
        "pubmed_id": {
          "anyOf": [
            {
              "pattern": "^[0-9]{1,20}$",
              "title": "PubMed Id",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "PubMed unique identifier (PMID) of the publication.",
          "title": "Pubmed Id"
        },
        "author_list": {
          "anyOf": [
            {
              "items": {
                "minLength": 2,
                "title": "Author",
                "type": "string"
              },
              "minItems": 1,
              "title": "Authors",
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of publication authors.",
          "title": "Author List"
        }
      },
      "required": [
        "title",
        "doi"
      ],
      "title": "Publication",
      "type": "object",
      "unique_value_contribution": [
        "doi"
      ]
    },
    "QuantitativeValue": {
      "properties": {
        "value": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "integer"
            },
            {
              "type": "number"
            },
            {
              "pattern": "^(?!^[-+.]*$)[+-]?0*\\d*\\.?\\d*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Value"
        },
        "unit": {
          "anyOf": [
            {
              "$ref": "#/$defs/UnitCvTerm"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Unit"
        }
      },
      "title": "QuantitativeValue",
      "type": "object"
    },
    "RawDataFile": {
      "description": "[MS, MS:1003083, raw data file]\nData file that contains original data as generated by an instrument,\nalthough not necessarily in the original data format\n(i.e. an original raw file converted to a different format is still a raw data file)",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "raw-data-file",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the file in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the file. File MUST be a file (not folder or link).It MAY be relative path (e.g., FILES/study.txt) or a file in a compressed file (e.g., FILES/study.zip#data/metadata.tsv).",
          "title": "Name"
        },
        "size": {
          "anyOf": [
            {
              "type": "integer"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The size of the file in bytes, representing the total amount of data contained in the file.",
          "title": "Size"
        },
        "hash_sha256": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The SHA-256 cryptographic hash of the file content, used to verify file integrity and ensure that the file has not been altered.",
          "title": "Hash Sha256"
        },
        "format_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to store the contents of the file, typically indicated by its extension (e.g., .txt, .csv, .mzML, .raw, etc.).",
          "title": "Format Ref"
        },
        "compression_format_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to compress the contents of the file, typically indicated by its extension (e.g., .zip, .tar, .gz, etc.). List item order shows order of compressions. e.g. [tar format, gzip format] for tar.gz",
          "title": "Compression Format Refs"
        },
        "extension": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The extension of file. It MUST contain all extensions (e.g., .raw, .mzML, .d.zip, .raw.zip, etc.).",
          "title": "Extension"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "RawDataFile",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Relationship": {
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^rel--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "relationship",
          "description": "The type property identifies type of the MHD Relationship Object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "source_ref": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            }
          ],
          "title": "Source Ref"
        },
        "relationship_name": {
          "title": "Relationship Name",
          "type": "string"
        },
        "target_ref": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            }
          ],
          "title": "Target Ref"
        },
        "source_role": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Source Role"
        },
        "target_role": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Target Role"
        }
      },
      "required": [
        "source_ref",
        "relationship_name",
        "target_ref"
      ],
      "title": "Relationship",
      "type": "object"
    },
    "ResultFile": {
      "description": "Processed result file (e.g. quantification or identification matrix).",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "result-file",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the file in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the file. File MUST be a file (not folder or link).It MAY be relative path (e.g., FILES/study.txt) or a file in a compressed file (e.g., FILES/study.zip#data/metadata.tsv).",
          "title": "Name"
        },
        "size": {
          "anyOf": [
            {
              "type": "integer"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The size of the file in bytes, representing the total amount of data contained in the file.",
          "title": "Size"
        },
        "hash_sha256": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The SHA-256 cryptographic hash of the file content, used to verify file integrity and ensure that the file has not been altered.",
          "title": "Hash Sha256"
        },
        "format_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to store the contents of the file, typically indicated by its extension (e.g., .txt, .csv, .mzML, .raw, etc.).",
          "title": "Format Ref"
        },
        "compression_format_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to compress the contents of the file, typically indicated by its extension (e.g., .zip, .tar, .gz, etc.). List item order shows order of compressions. e.g. [tar format, gzip format] for tar.gz",
          "title": "Compression Format Refs"
        },
        "extension": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The extension of file. It MUST contain all extensions (e.g., .raw, .mzML, .d.zip, .raw.zip, etc.).",
          "title": "Extension"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "ResultFile",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Revision": {
      "properties": {
        "revision": {
          "title": "Revision",
          "type": "integer"
        },
        "revision_datetime": {
          "format": "date-time",
          "title": "Revision Datetime",
          "type": "string"
        },
        "comment": {
          "title": "Comment",
          "type": "string"
        }
      },
      "required": [
        "revision",
        "revision_datetime",
        "comment"
      ],
      "title": "Revision",
      "type": "object"
    },
    "Sample": {
      "description": "A biological sample prepared for analytical measurement.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "sample",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name or identifier of the sample.",
          "title": "Name"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the sample in the repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "additional_identifier_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/CvTermValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of additional secondary identifiers for the sample.",
          "title": "Additional Identifier List"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Sample",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "SampleRun": {
      "description": "An analytical run representing the measurement of a sample on an instrument.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "sample-run",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the sample run in the repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name or label of the sample run.",
          "title": "Name"
        },
        "sample_ref": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the sample object measured in this run.",
          "title": "Sample Ref"
        },
        "sample_run_configuration_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of configuration object IDs for the sample run.",
          "title": "Sample Run Configuration Refs"
        },
        "raw_data_file_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of raw data file object IDs produced by the sample run.",
          "title": "Raw Data File Refs"
        },
        "derived_data_file_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of derived data file object IDs generated from the sample run.",
          "title": "Derived Data File Refs"
        },
        "result_file_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of result file object IDs produced from the sample run.",
          "title": "Result File Refs"
        },
        "supplementary_file_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of supplementary file object IDs associated with the sample run.",
          "title": "Supplementary File Refs"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "SampleRun",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "SampleRunConfiguration": {
      "description": "Configuration settings and instrument parameters used for a sample run.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "sample-run-configuration",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the sample run configuration in the repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "protocol_ref": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the protocol object defining the run configuration.",
          "title": "Protocol Ref"
        },
        "parameter_value_refs": {
          "anyOf": [
            {
              "items": {
                "anyOf": [
                  {
                    "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                    "type": "string"
                  },
                  {
                    "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                    "type": "string"
                  },
                  {
                    "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                    "type": "string"
                  }
                ]
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of parameter value object IDs specifying run parameters.",
          "title": "Parameter Value Refs"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "SampleRunConfiguration",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Specimen": {
      "description": "A biological specimen collected from a subject.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "specimen",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name or identifier of the specimen.",
          "title": "Name"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the specimen in the repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "additional_identifier_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/CvTermValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of additional secondary identifiers for the specimen.",
          "title": "Additional Identifier List"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Specimen",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "Study": {
      "description": "A biological research study or experiment comprising samples, protocols, and data.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "study",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "mhd_identifier": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Unique MetabolomicsHub Data (MHD) identifier for the study.",
          "title": "Mhd Identifier"
        },
        "doi": {
          "anyOf": [
            {
              "pattern": "^10[.].+/.+$",
              "title": "DOI",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Digital Object Identifier (DOI) for the study.",
          "title": "Doi"
        },
        "repository_identifier": {
          "description": "Accession number or identifier in the source repository.",
          "minLength": 2,
          "title": "Repository Identifier",
          "type": "string"
        },
        "additional_identifier_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/CvTermValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of additional database or secondary identifiers for the study.",
          "title": "Additional Identifier List"
        },
        "title": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Title of the study.",
          "title": "Title"
        },
        "description": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Detailed abstract or summary description of the study.",
          "title": "Description"
        },
        "submission_date": {
          "anyOf": [
            {
              "format": "date-time",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Date and time when the study was submitted.",
          "title": "Submission Date"
        },
        "public_release_date": {
          "anyOf": [
            {
              "format": "date-time",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Date and time when the study was publicly released.",
          "title": "Public Release Date"
        },
        "license": {
          "anyOf": [
            {
              "format": "uri",
              "maxLength": 2083,
              "minLength": 1,
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Data license or URL defining usage rights for the study.",
          "examples": [
            "https://creativecommons.org/publicdomain/zero/1.0/"
          ],
          "title": "License"
        },
        "grant_identifier_list": {
          "anyOf": [
            {
              "items": {
                "minLength": 2,
                "title": "Grant Identifier",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of grant identifiers funding the study.",
          "title": "Grant Identifier List"
        },
        "dataset_url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of dataset access or repository URLs.",
          "title": "Dataset Url List"
        },
        "related_dataset_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of related dataset key-value pairs.",
          "title": "Related Dataset List"
        },
        "protocol_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of protocol object IDs used in the study.",
          "title": "Protocol Refs"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Study",
      "type": "object",
      "unique_value_contribution": [
        "mhd_identifier",
        "repository_identifier"
      ]
    },
    "Subject": {
      "description": "An individual organism or subject from which biological samples are derived.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "subject",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name or identifier of the subject.",
          "title": "Name"
        },
        "subject_type_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Reference ID to the subject type CV term object.",
          "title": "Subject Type Ref"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the subject in the repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "additional_identifier_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/CvTermValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "List of additional secondary identifiers for the subject.",
          "title": "Additional Identifier List"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "Subject",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "SupplementaryFile": {
      "description": "Supplementary document or asset file associated with the dataset.",
      "properties": {
        "id": {
          "anyOf": [
            {
              "pattern": "^mhd--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property uniquely identifies the object.",
          "title": "Id"
        },
        "type": {
          "anyOf": [
            {
              "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": "supplementary-file",
          "description": "The type property identifies type of the object",
          "title": "Type"
        },
        "created_by_ref": {
          "anyOf": [
            {
              "pattern": "^cv-value--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The id property of the data-provider who created the object.",
          "title": "Created By Ref"
        },
        "tag_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Key-value tags related to the object.",
          "title": "Tag List"
        },
        "external_reference_list": {
          "anyOf": [
            {
              "items": {
                "$ref": "#/$defs/KeyValue"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "External references related to the object.",
          "title": "External Reference List"
        },
        "url_list": {
          "anyOf": [
            {
              "items": {
                "format": "uri",
                "minLength": 1,
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "URL list related to the object.",
          "title": "Url List"
        },
        "label": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "title": "Label"
        },
        "repository_identifier": {
          "description": "Unique identifier assigned to the file in the source repository.",
          "title": "Repository Identifier",
          "type": "string"
        },
        "name": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "Name of the file. File MUST be a file (not folder or link).It MAY be relative path (e.g., FILES/study.txt) or a file in a compressed file (e.g., FILES/study.zip#data/metadata.tsv).",
          "title": "Name"
        },
        "size": {
          "anyOf": [
            {
              "type": "integer"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The size of the file in bytes, representing the total amount of data contained in the file.",
          "title": "Size"
        },
        "hash_sha256": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The SHA-256 cryptographic hash of the file content, used to verify file integrity and ensure that the file has not been altered.",
          "title": "Hash Sha256"
        },
        "format_ref": {
          "anyOf": [
            {
              "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to store the contents of the file, typically indicated by its extension (e.g., .txt, .csv, .mzML, .raw, etc.).",
          "title": "Format Ref"
        },
        "compression_format_refs": {
          "anyOf": [
            {
              "items": {
                "pattern": "^cv--[-a-zA-Z0-9]+--[0-9a-f]{8}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{4}-[0-9a-f]{12}$",
                "type": "string"
              },
              "type": "array"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The structure or encoding used to compress the contents of the file, typically indicated by its extension (e.g., .zip, .tar, .gz, etc.). List item order shows order of compressions. e.g. [tar format, gzip format] for tar.gz",
          "title": "Compression Format Refs"
        },
        "extension": {
          "anyOf": [
            {
              "type": "string"
            },
            {
              "type": "null"
            }
          ],
          "default": null,
          "description": "The extension of file. It MUST contain all extensions (e.g., .raw, .mzML, .d.zip, .raw.zip, etc.).",
          "title": "Extension"
        }
      },
      "required": [
        "repository_identifier"
      ],
      "title": "SupplementaryFile",
      "type": "object",
      "unique_value_contribution": [
        "repository_identifier"
      ]
    },
    "UnitCvTerm": {
      "properties": {
        "source": {
          "default": "",
          "description": "Ontology source name.",
          "title": "Source",
          "type": "string"
        },
        "accession": {
          "default": "",
          "description": "Accession number of CV term in compact URI format.",
          "title": "Accession",
          "type": "string"
        },
        "name": {
          "default": "",
          "description": "Label of CV term.",
          "title": "Name",
          "type": "string"
        }
      },
      "title": "UnitCvTerm",
      "type": "object"
    }
  },
  "properties": {
    "repository_name": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Repository Name"
    },
    "mhd_identifier": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Mhd Identifier"
    },
    "repository_identifier": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Repository Identifier"
    },
    "revision": {
      "anyOf": [
        {
          "type": "integer"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Revision"
    },
    "revision_datetime": {
      "anyOf": [
        {
          "format": "date-time",
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Revision Datetime"
    },
    "repository_revision": {
      "anyOf": [
        {
          "type": "integer"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Repository Revision"
    },
    "repository_revision_datetime": {
      "anyOf": [
        {
          "format": "date-time",
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Repository Revision Datetime"
    },
    "change_log": {
      "anyOf": [
        {
          "items": {
            "$ref": "#/$defs/Revision"
          },
          "minItems": 1,
          "type": "array"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Revision",
      "title": "Change Log"
    },
    "$schema": {
      "description": "Schema name of the file",
      "title": "Schema Name",
      "type": "string"
    },
    "profile_uri": {
      "description": "Validation Profiles",
      "title": "Profile Uri",
      "type": "string"
    },
    "cv_definitions": {
      "default": [],
      "items": {
        "$ref": "#/$defs/CvDefinition"
      },
      "title": "Cv Definitions",
      "type": "array"
    },
    "id": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Unique identifier of graph node",
      "title": "Id"
    },
    "type": {
      "default": "base-dataset",
      "pattern": "^[a-z0-9]+(?:-[a-z0-9]+)*$",
      "title": "Type",
      "type": "string"
    },
    "name": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Name"
    },
    "description": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "title": "Description"
    },
    "graph": {
      "$ref": "#/$defs/MhdGraph",
      "default": {
        "start_item_refs": [],
        "nodes": [],
        "relationships": []
      },
      "mhdGraphValidation": {},
      "title": "Graph"
    }
  },
  "required": [
    "$schema",
    "profile_uri"
  ],
  "title": "MhDatasetBaseProfile",
  "type": "object"
}